TABLE 1.
Cancer type | Property | Studied species and biomaterial | Expression | Prognosis | Number of cases | Refs |
---|---|---|---|---|---|---|
Lung cancer | Suppressor | Human tumorous tissue | Down | Favorable | 24 | Hosseini et al. (2018) |
Oncogene | NSCLC cell lines and body fluid | Down | Poor | — | Li et al. (2017) | |
Suppressor | Human NSCLC tissue and cell lines | Down | Favorable | 80 | Zeng et al. (2020) | |
— | HEK 293T cells | Down | — | — | Chen et al. (2015) | |
— | Human NSCLC tissue and cell lines | Down | — | — | Gao et al. (2018) | |
Suppressor | Human NSCLC tissue | Down | Favorable | 81 | Zhang et al. (2017) | |
Suppressor | Human LUSC cell lines | Down | Favorable | — | Qi et al. (2021) | |
Suppressor | Human LUAD tissue and cell lines | Down | Favorable | 20 | Zhao et al. (2021) | |
Suppressor | Human NSCLC cell lines | Down | — | — | Chen et al. (2021) | |
Gallbladder carcinoma | Suppressor | Human GBC tissue and cell lines | Down | Favorable | 53 | He et al. (2018) |
Cholangiocarcinoma | Oncogene | Human bile and serum | Up | Poor | 106 | Han et al. (2020a) |
Rectal cancer | — | Human CRC tissue and cell lines | Down | — | — | Bjørnetrø et al. (2019) |
Colon cancer | — | Human tumorous tissue | — | — | 396 | Jacob et al. (2017) |
Suppressor | Human tumorous tissue and cell lines | Down | Favorable | 60 | Yu et al. (2018) | |
Prostate cancer | Suppressor | Human PCa tissue and PC cell lines | Down | Favorable | 40 | Song et al. (2018) |
— | Human PCa cell lines | Down | — | — | Kumar et al. (2016) | |
— | Human seminal fluid and PCa cell lines | Down | Favorable | 24 | Barceló et al. (2020) | |
Esophageal squamous cell carcinoma | — | Human serum | Up | Poor | 30 | Zhu et al. (2017) |
Suppressor | Human ESCC tissue and cell lines | Down | Favorable | 144 | Guo et al. (2021) | |
Suppressor | Human ESCC tissue and cell lines | Down | Favorable | 64 | Wang et al. (2020) | |
Ovarian cancer | Suppressor | The meta-analysis | Down | Favorable | — | Shi et al. (2018) |
Cervical cancer | — | Human tumorous tissue | Down | Favorable | 121 | Zheng et al. (2019) |
Breast cancer | — | Human tumorous tissue | Down | Favorable | 96 | Kunc et al. (2020) |
Renal cell carcinoma | Suppressor | Human RCC tissue and cell lines | Down | Favorable | 25 | Liang et al. (2021) |
Pancreatic cancer | Suppressor | Pancreatic cancer cell | Down | Favorable | — | Zheng et al. (2021) |
Osteosarcoma | Oncogene | Human cell line HFOB1.19 | Up | Poor | — | Hu Y. et al. (2021) |
Thyroid cancer | Suppressor | Cell lines | Down | — | — | Hu C. et al. (2021) |
Hepatocellular carcinoma | Suppressor | Human HCC tissue | Down | Favorable | 36 | Yu et al. (2019) |
Suppressor | Human HCC tissue and cell lines | Down | Favorable | 25 | Zhuang et al. (2019) |