Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Cartoon illustrating morphological changes in outflow cushion/valve formation. The outflow cushions first appear at CS12-14 (equivalent to mouse E10-E11). Between CS15-18, the distal parts of the cushions remodel to form the valve precursors. From CS19 onwards, these valve precursors are sculpted to produce the thin valve leaflets with the sinus behind. Blue denotes the outflow wall. Red denotes the endocardium.
