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. 2022 Jan 27;8:805612. doi: 10.3389/fnut.2021.805612

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Copyright © 2022 Yong, Fang, Huang, Li, Yu, Wu, Hu, Liu, Yu, Ma, Gooneratne, Li, Abd El-Aty and Ju.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The putative signal pathway of terpinen-4-ol (TER) protects gut integrity in IPEC-J2 cells. TER attenuated LPS induces downregulation of tight junction proteins via the ERK1/2 signal pathway.