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. 2022 Jan 27;8:805612. doi: 10.3389/fnut.2021.805612

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Copyright © 2022 Yong, Fang, Huang, Li, Yu, Wu, Hu, Liu, Yu, Ma, Gooneratne, Li, Abd El-Aty and Ju.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of TER on LPS-induced intestinal epithelial cell permeability and inflammatory cytokines. The protective effects of TER on fused monolayers of intestinal epithelial cells were examined by measuring the TEER values of fused intestinal epithelial monolayers at different time points and FITC-dextran permeability. (A) TEER values. Cells were treated with LPS on day 17 after differentiation, and TEER values were detected at different times (B–D). Cell permeability was measured by determining FITC-dextran permeability after 24 h of LPS exposure in TER-treated cells (E). The IL-6 (F) and TNF-α (G) levels in the culture supernatants of cells pretreated with TER for 24 h and then exposed to LPS for 3 h were measured by ELISA. ** and ## display similar means with above mentioned.