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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Acta Biomater. 2021 Oct 25;140:43–75. doi: 10.1016/j.actbio.2021.10.030

Table 1.

Summary of the classes of assembling peptides reviewed here, including the peptide family, the class of assembling peptide to which the family belongs, and selected key references.

Peptide family Type Examples sequences Ref.
EAK16 Amphipathic β-sheet Ac-(AEAEAKAK)2-NH2 16, 38
RADA16 Amphipathic β-sheet Ac-(RARADADA)2-NH2 38, 44, 45
KFE Amphipathic β-sheet Ac-(FKFE)3-NH2 33, 88, 89
MAX Amphipathic β-sheet Ac-VKVKVKVKVDPPTKVKVKVKV-NH2 17, 18, 48, 49
E1Y9 Amphipathic β-sheet Ac-EYEYKYEYKY-NH2 50, 51
Q11 Amphipathic β-sheet Ac-QQKFQFQFEQQ-NH2 5255
Diphenylalanine Short aromatic β-sheet Ac-FF-COOH 69, 70, 71,73, 79
Tripeptides Short aromatic β-sheet YFD, FYD, DFY, DYF, KYF, KYY, KFF, KYW 8082
RAPID Short aromatic β-sheet KYFIL, AYFIL, KYFAL 32, 83
Metal-ion binding Metal-ion induced β-sheet Pyrene-CGPC, ILVAGH, GQ(PHGGGWQG)4CG 35, 9799
Coiled coils Helical Ac-GYK(IAALKEK)2-IAALKEG-NH2, Ac-GYE(IAALEKE)2-IAALEKG-NH2 27, 105, 108111, 114, 115
Collagen-like Helical Ac-(GPO)8-GG-NH2, Ac-(GPO)3-GAO-(GPO)4-GG-NH2 139142
Peptide amphiphiles Lipid-tail β-sheet Lipid-CCCCGGGJRGD, Lipid-GGGGGGGERGDS 166168, 171,172
Block copolypeptides Multiple K180L20, K180L40K180 181184
Elastin-like peptides Intrinsically disordered VPGPG 188190, 192, 193, 201,202