Table 1.
Gene | B Cells | T Cells | Natural Killer Cells | Myeloid | Repressor or Activator? |
---|---|---|---|---|---|
ciita | Yes | Not expressed | n.e. | n.e. | Repressor |
pax-5 | Yes | Not expressed | n.e. | Not expressed | Repressor |
igh | Yes | Not expressed | Not expressed | Not expressed | Activator |
spiB | Yes | n.e. | n.e. | n.e. | Repressor |
bcl6 | Yes | Yes | n.e. | Yes | Repressor |
c-myc | Yes | No | n.e. | Yes | Repressor |
il6 | n.e. | n.e. | n.e. | Yes | Repressor |
Il10 | n.e. | Yes | n.e. | n.e. | Activator |
Il2 | n.e. | Yes | n.e. | n.e. | Repressor |
Tnf | n.e. | n.e. | Yes | n.e. | Repressor |
Reported direct targets of Blimp1 transcriptional regulation in immune cell subsets (*n.e., not evaluated).