Table 1.
The distribution of differentially expressed miRNA identified in each RNA-seq dataset.
| Dataset | Tissue type/biospecimen | # DE-miRNAa | # Upregulated | # Downregulated | p-valueb |
|---|---|---|---|---|---|
| GSE139577 | Circulatory | 174 | 80 | 94 | 0.1339 |
| GSE109266 | Circulatory | 838 | 207 | 631 | <0.0001 |
| GSE90028 | Circulatory | 172 | 99 | 73 | 0.0051 |
| GSE174502 | Adipose | 62 | 45 | 17 | <0.0001 |
| GSE52314 | Pancreatic | 10 | 4 | 6 | 0.3833 |
| Totalc | – | 1256 | 435 | 821 | <0.0001 |
a: defined as miRNA with absolute log2 fold change >1 and Benjamini- Hochberg adjusted p-value < 0.05; b: computed by chi-squared test for two proportions; c: including genes commonly expressed across multiple tissues.
DE-miRNA: differentially expressed miRNA.