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. 2021 Apr 8;22(4):280–287. doi: 10.1177/17511437211010031

Table 7.

Separation of intervention groups in terms of arterial partial pressure of oxygen for recent trials of conservative oxygen therapy.

Trial Intervention group Target SpO2 Median PaO2 (kPa) Group PaO2 separation (kPa)
This study (Martin et al.) Conservative O2 88–92% 8.6 3.2
Control Usual care 11.8
Girardis et al. 6 Conservative O2 94–98% 11.6 2.0
Control Usual care 13.6
Mackle et al. 7 Conservative O2 91–96% 10.9a 1.6
Control ≥91% 12.5a
Barrot et al. 8 Conservative O2 88–92% 9.3a 4.6
Control ≥96% 13.9a

Median PaO2 and group separation in controlled trials of conservative oxygen therapy in Critical Care settings. The values for means for Mackle et al and Barrot et al’s studies were estimated from graphs in supplemental appendices provided with the manuscripts.

aConverted to kPa if expressed as mmHg.