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. 2022 Feb 9;12(2):e054669. doi: 10.1136/bmjopen-2021-054669

Table 1.

Incidence by age and sex per 100 000 person-years

Sex Age Total
26–35 36–45 46–55 56–64
VTE (DVT OR PE)
Female 95.26* 161.16* 235.13 374.65 224.14
Male 51.31 105.99 221.53 416.33 203.74
Total 72.43 132.87 228.27 395.31 213.79
VTE+a (DVT+a OR PE+a)
Female 51.68* 90.02* 130.21 214.42 126.03
Male 29.78 65.90 143.87 276.78 132.56
Total 40.31 77.66 137.10 245.32 129.34
CVT
Female 8.61 8.93 8.07 8.25 8.45
Male 2.54 2.70 4.52 7.39 4.36
Total 5.46 5.74 6.28 7.82 6.37
Any major venous thrombosis (DVT, CVT and other)†
Female 113.72 187.86 272.82 426.94 258.85
Male 61.13 123.55 255.92 485.99 237.27
Total 86.40 154.87 264.29 456.20 247.89
ITP
Female 30.38 27.09 27.80 38.23 30.99
Male 9.73 13.06 20.77 39.97 21.29
Total 19.66 19.90 24.25 39.09 26.06
HUS
Female 0.96 1.08 1.38 1.51 1.25
Male 0.38 0.56 0.75 0.78 0.63
Total 0.66 0.81 1.07 1.15 0.94
HIT
Female 1.52 1.92 4.01 9.41 4.41
Male 0.58 1.99 5.24 12.43 5.22
Total 1.03 1.96 4.63 10.90 4.82

*Does not include pregnancy-related events.

†Any major venous thrombosis: VTE, CVT, portal vein thrombosis, hepatic vein thrombosis/Budd-Chiari syndrome, thrombophlebitis migrans, embolism or thrombosis of vena cava (inferior), embolism or thrombosis of renal vein or mesenteric thrombosis.

CVT, cerebral venous thrombosis; DVT, deep vein thrombosis; HIT, heparin-induced thrombocytopenia; HUS, haemolytic-uremic syndrome; ITP, immune thrombocytopenic purpura; PE, pulmonary embolism; VTE, venous thromboembolism.