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. 2020 Dec 18;2020(12):CD008500. doi: 10.1002/14651858.CD008500.pub5

Comparison 9. Anticoagulants versus control: incidental venous thromboembolism.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
9.1 Incidental VTE: DOAC vs placebo 2 1404 Risk Ratio (IV, Random, 95% CI) 0.50 [0.25, 0.98]
9.1.1 Apixaban 1 563 Risk Ratio (IV, Random, 95% CI) 0.48 [0.12, 1.89]
9.1.2 Rivaroxaban 1 841 Risk Ratio (IV, Random, 95% CI) 0.50 [0.23, 1.10]
9.2 Incidental VTE: LMWH vs no thromboprophylaxis 5 4452 Risk Ratio (IV, Random, 95% CI) 0.63 [0.40, 0.99]
9.2.1 Dalteparin 3 2419 Risk Ratio (IV, Random, 95% CI) 0.58 [0.34, 1.00]
9.2.2 Nadroparin 1 1150 Risk Ratio (IV, Random, 95% CI) 0.74 [0.21, 2.62]
9.2.3 Certoparin 1 883 Risk Ratio (IV, Random, 95% CI) 0.75 [0.26, 2.14]
9.3 Incidental VTE: prophylactic vs intermediate or therapeutic LMWH 1   Risk Ratio (IV, Fixed, 95% CI) Subtotals only
9.3.1 Prophylactic vs intermediate 1 51 Risk Ratio (IV, Fixed, 95% CI) 2.89 [0.12, 67.75]
9.3.2 Prophylactic vs therapeutic 1 52 Risk Ratio (IV, Fixed, 95% CI) 3.00 [0.13, 70.42]
9.4 Incidental VTE: semuloparin vs placebo 1 3212 Risk Ratio (IV, Fixed, 95% CI) 0.14 [0.01, 2.76]