Skip to main content
. 2020 Dec 18;2020(12):CD008500. doi: 10.1002/14651858.CD008500.pub5

Comparison 10. Anticoagulants versus control: minor bleeding.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
10.1 Minor bleeding: LMWH vs no thromboprophylaxis 8 2901 Risk Ratio (IV, Random, 95% CI) 1.24 [0.92, 1.68]
10.1.1 Dalteparin 5 815 Risk Ratio (IV, Random, 95% CI) 1.32 [0.77, 2.24]
10.1.2 Nadroparin 1 1150 Risk Ratio (IV, Random, 95% CI) 1.00 [0.69, 1.45]
10.1.3 Certoparin 1 898 Risk Ratio (IV, Random, 95% CI) 1.96 [1.11, 3.46]
10.1.4 Bemiparin 1 38 Risk Ratio (IV, Random, 95% CI) 0.45 [0.09, 2.17]
10.2 Minor bleeding: prophylactic vs intermediate or therapeutic LMWH 1   Risk Ratio (IV, Fixed, 95% CI) Subtotals only
10.2.1 Prophylactic vs intermediate 1 51 Risk Ratio (IV, Fixed, 95% CI) Not estimable
10.2.2 Prophylactic vs therapeutic 1 52 Risk Ratio (IV, Fixed, 95% CI) 0.20 [0.01, 3.97]
10.3 Minor bleeding: LMWH vs aspirin 2 781 Risk Ratio (IV, Random, 95% CI) 0.70 [0.17, 2.84]
10.4 Minor bleeding: LMWH vs warfarin 1 439 Risk Ratio (IV, Fixed, 95% CI) 3.01 [0.32, 28.75]
10.5 Minor bleeding: UFH vs no thromboprophylaxis 1 277 Risk Ratio (IV, Fixed, 95% CI) 3.02 [0.12, 73.54]
10.6 Minor bleeding: vitamin K antagonists vs placebo 1 311 Risk Ratio (IV, Fixed, 95% CI) 2.44 [0.64, 9.27]
10.7 Minor bleeding: warfarin vs aspirin 1 440 Risk Ratio (IV, Fixed, 95% CI) 0.17 [0.02, 1.37]