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. 2020 Dec 18;2020(12):CD008500. doi: 10.1002/14651858.CD008500.pub5

Comparison 13. Anticoagulants versus control: serious adverse events.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
13.1 Serious adverse events: DOAC vs placebo 2 934 Risk Ratio (IV, Random, 95% CI) 0.96 [0.82, 1.13]
13.2 Serious adverse events: LMWH vs no thromboprophylaxis 5 1531 Risk Ratio (IV, Random, 95% CI) 0.86 [0.70, 1.07]
13.2.1 Dalteparin 3 343 Risk Ratio (IV, Random, 95% CI) 1.22 [0.45, 3.34]
13.2.2 Nadroparin 1 1150 Risk Ratio (IV, Random, 95% CI) 0.89 [0.68, 1.17]
13.2.3 Bemiparin 1 38 Risk Ratio (IV, Random, 95% CI) 0.75 [0.43, 1.30]
13.3 Serious adverse events: semuloparin vs placebo 1 3172 Risk Ratio (IV, Fixed, 95% CI) 1.03 [0.92, 1.16]