NCT02285738.

Study name	Anti‐platelet and statin therapy to prevent cancer‐associated thrombosis: a pilot study
Methods	Open‐label, parallel‐assignment RCT
Participants	Patients with a histological diagnosis of malignancy of a solid organ or lymphoma who have a VTE risk score of ≥ 1 and will be initiating a new systemic chemotherapy regimen
Interventions	Intervention 1: aspirin Intervention 2: simvastatin Control: observation
Outcomes	Primary outcome: change in average soluble P‐selectin levels Secondary outcomes: major bleeding complications or clinically significant non‐bleeding complications; change in circulating biomarkers; thrombotic events including venous thrombosis, PE, visceral vein thrombosis; arterial thromboembolic events including stroke, myocardial infarction, or arterial embolism
Starting date	December 2014
Contact information
Notes	ClinicalTrials.gov identifier: NCT02285738