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. 2022 Jan 27;12:792139. doi: 10.3389/fphar.2021.792139

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Copyright © 2022 Ren, Wang, Guo, Huang, Tan, Ma and Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of PEC on the activation of TGF-β/SMAD3 and JAK2/STAT3 signaling pathways in UA-stimulated TCMK-1 cells. (A,B) The TGF-β and p-Smad3/Smad3 protein levels normalized by GAPDH. (C,D) The p-IAK2/JAK2 and p-STAT3/STAT3 protein levels normalized by α-tubulin. All data are represented as the mean ± SD (n = 3). ****p < 0.0001.