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. 2022 Jan 27;12:792139. doi: 10.3389/fphar.2021.792139

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Copyright © 2022 Ren, Wang, Guo, Huang, Tan, Ma and Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of PEC on gene expression in kidneys of HN mice. (A) Volcano plot of gene expression difference between Control and HN groups. (B) Differentially regulated genes difference between Control, HN, and PEC 25 mg/kg. (C) Heatmap of gene expression difference among Control, HN, and PEC 25 mg/kg. (D) GO analysis of differentially expressed genes. (E) KEGG analysis of differentially expressed genes.