TABLE 3.
Summary of pathological changes noted in tissues examined from three calves in group L and two calves in group B 6 months after inoculation with M. avium subsp. paratuberculosis
| Animal no. | Scorea
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Jejunum
|
ICV
|
ICLN
|
||||||||
| Villi
|
Lymphoid tissue
|
Villi
|
Lymphoid tissue
|
|||||||
| Pathology | AFB | Pathology | AFB | Pathology | AFB | Pathology | AFB | Pathology | AFB | |
| L7 | − | − | − | − | ++ | + | + | − | + | + |
| L5 | − | − | − | − | ++ | ++ | − | − | − | − |
| L6 | − | − | − | − | − | − | − | − | − | + |
| B3 | ++ | − | ++ | + | ++ | + | + | − | +++ | ++ |
| B2 | − | − | − | − | − | − | + | − | +++ | + |
a
The scoring systems were as follows. Pathology: +, 1 or 2 small granulomata; ++, between 2 and 10 granulomata; +++, more than 10 granulomata. AFB: +, 1 to 5 clumps of bacteria identified; ++, moderate numbers of AFB present; +++, abundant numbers of AFB present.