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. 2004 Oct 18;2004(4):CD004554. doi: 10.1002/14651858.CD004554.pub2

Im 2002.

Methods Randomised double‐blind parallel group study. Method of randomisation not stated. 
 Multi‐centred, South Korea. 
 Method of data analysis not stated. 
 Duration: 2 months
Participants 197 patients, no withdrawals noted. No baseline characteristics available. Inclusion criteria: PD patients experiencing end‐of‐dose deterioration.
Interventions Patients recieved entacapone (dose not given; n=98) or placebo (n=99) as an adjunct to levodopa (with each dose?).
Outcomes 'On' time 
 'Off' time 
 Levodopa dose 
 Total UPDRS 
 UPDRS motor 
 CGI 
 Adverse events
Notes ENTACAPONE 
 Abstract only 
 Dose not given
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear