Table 1.

Chemical Structures and Human D₂-Like Receptor Binding Affinity Data of Newly Developed Analogues^a

^aThe values represent the arithmetic mean ± SEM of triplicate determinations from at least three independent experiments. IC₅₀ values for each compound were determined from dose−response curves, and K_i values were calculated by the Cheng−Prusoff equation⁴³ using GraphPad Prism version 6.00 for Macintosh. n = number of independent experiments, each performed in triplicate.

^bCompound reported in ref 39.