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. 2022 Jan 27;12:766150. doi: 10.3389/fpsyt.2021.766150

Table 2.

Overview of the characteristics and findings from the identified systematic reviews.

Review Type Inclusion criteria Period Outcomes Aims Study quality Study characteristics Findings summary
Boudreau et al. (47) NQ Peer-Mediated; Age range 4–18 years; Design: no design restrictions NR SC Evaluate peer-mediated PRT for facilitating the SC of school-aged children with ASD Modified/expanded (by authors) framework for appraising the quality of evidence Reichow et al. (50) N = 5 studies; N = 10 participants (8 after removing overlap); Age: 7–10 years; IQ: 55–85 None of the studies met the criteria for classification as promising or established EBP for improving SC impairments
Bozkus-Genc and Yucesoy-Ozkan (28) M Design: Single-case; Age range: 1–13 years 1979–2012 No restrictions Evaluate participant and intervention characteristics, effectiveness and moderators NA N = 34 studies; Age: 2 years, 5 months-12 years, 8 months; Settings: multiple (44.1%), clinic (26.4%), school (14.7%), home (8.8%), community (5.8%) Mean PND: 76.10% (SD = 33.65, range: 0–100); effect sizes > 90% in 38.2% of studies, 70–89% in 33.4% of studies, and <70% in 29.4% of studies; PND scores >70% for all of the dependent variables except play and social skills. 14 studies labeled as highly effective, 11 fairly effective, 10 questionable/ineffective.
Mean PNCD: 78.03% (SD = 34.38, range: 0-100); effect sizes > 90% in 41.1% of studies, 70–89% in 26.5% of studies, and <70% in 26.4% of studies; PNCD scores >70% for all of the dependent variables except play skills. 14 studies labeled as highly effective, 9 fairly effective, 10 questionable/ineffective.
Mean PEM: 89.34% (SD = 22.18, range: 0-100); effect sizes > 90% in 79.4% of studies, 70–89% in 11.7% of studies, and <70% in 8.8% of studies; PEM scores >70% for all of the dependent variables. 27 studies labeled as highly effective, 4 fairly effective, 3 questionable/ineffective.
Cardogan and McCrimmon (48) NQ <18 years of age NR Study quality Evaluate adherence of PRT studies to specific research quality standards Seven specific standards chosen by authors N = 17 studies Systematic application of an intervention procedure: five studies utilized a pre–post evaluation, 11 multiple baseline procedure, one did not collect any baseline data; Comparison of intervention approaches: two studies compared intervention approaches;
Use of standard intervention protocols: 9 studies explicitly aligned with the PRT manuals;
Treatment fidelity: two studies adhered to the recommended fidelity standard prior to the study start but there were variations during the intervention, five studies no reference to the fidelity measures;
Use of objective evaluators: 11 studies used objective evaluators, remaining studies did not reference the use of objective evaluators (two did not require it given the design);
Inter-rater reliability: 12 studies reported some form of inter-rater reliability;
Longitudinal studies: 8 studies collected follow-up data after the post-treatment stage and 9 did not.
Forbes et al. (49) NQ Design: Experimental; Other: at least one communication skill as a dependent variable 1987–2018 Communication Evaluate primary linguistic and verbal behavior outcomes following PRT and how generalized and collateral outcomes were reported NA N = 50 studies The majority of studies aggregated results and/or did not report sufficient detail to determine linguistic forms and/or verbal behavior functions;
There was evidence for the generalization of communication skills to untargeted people, settings, materials, and/or activities;
Only one study indicated untargeted linguistic forms emerged following PRT and none of the studies described results that indicated improved generalized and collateral verbal behavior functions.
Ona et al. (46) M Design: RCT; Age range: ≤ 18 years of age up to August 2017 SC, SI, RRB Evaluate social communication, social interaction, and repetitive behavior outcomes in PRT RCTs GRADE N = 7 studies; N = 181 participants; Age: 2.4–9.2 years Communication (subjective report): two studies, SMD 1.12 (95% CI −0.49; 2.73), p = 0.17, GRADE: very low;
Expressive language (subjective report): one study, SMD 0.45 (95% CI −0.13; 1.03), p = 0.13, GRADE: low;
Expressive language (direct measurement): two studies, SMD 0.48 (95% CI.04; 0.93), p = 0.03, GRADE: low;
Receptive language (subjective report): one study, SMD 0.22 (−0.35; 0.79), p = 0.45, GRADE: low; Social Interaction: one study (subjective report): SMD 0.48 (−1.10; 1.06), p = 0.10, SMD 0.46 (−0.12; 1.04), p = 0.12 for CGI-S and SMD 1.12 (0.50; 1.74), p = 0.0004 for CGI-I
Repetitive Behaviors (direct assessment): one study, SMD 15.97 (95% CI 11.57 to 20.36) p <0.0001, GRADE: low.
Verschuur et al. (37) NQ Age: no constraints; Design: no constraints Up to June 2014 No restrictions Evaluate: the range of targeted skills; PRT effectiveness for improving children's outcomes; PRT effectiveness for improving parental and staff outcomes and skills; the certainty of evidence; identify limitations and future directions Quality of evidence (51); Certainty of evidence following classification by Ramdoss et al. (52) into suggestive, preponderant and conclusive N = 37 studies N = 420 participants; Age: 1–12.7 years 56.4% of studies had serious methodological limitations;
43.6% of studies showed conclusive or preponderant evidence that PRT increases self-initiations and results in collateral improvements in communication and language, play skills, affect and reductions in maladaptive behavior;
The majority of caregivers and staff members were able to implement PRT techniques;
Few studies reported on collateral improvements in caregivers' and staff members' behaviors and evidence was qualified as sparse.

GRADE, Grading of Recommendation, Assessment, Development and Evaluation; M, meta-analysis; NQ, non-quantitative; NR, not reported; PEM, percentage of data points exceeding median; PNCD, percentage of nonoverlapping corrected data; PND, percentage of nonoverlapping data; PRT, Pivotal Response Training; SC, social and communication; SI, social interaction; SMD, standardized mean difference.