Table 2.
Correction between log-transformed angiopoietin-like protein 3 level and clinical variables
| Variables | Spearman’s correlation coefficient | P |
|---|---|---|
| Age (years) | −0.160 | 0.132 |
| Height (cm) | −0.176 | 0.098 |
| Body weight (kg) | −0.081 | 0.449 |
| Waist circumference (cm) | 0.075 | 0.481 |
| BMI (kg/m2) | 0.019 | 0.861 |
| Systolic blood pressure (mmHg) | 0.124 | 0.243 |
| Diastolic blood pressure (mmHg) | 0.007 | 0.950 |
| Total cholesterol (mg/dL) | 0.111 | 0.296 |
| Log-triglyceride (mg/dL) | 0.258 | 0.014* |
| HDL-C (mg/dL) | −0.230 | 0.030* |
| LDL-C (mg/dL) | 0.226 | 0.032* |
| Log-glucose (mg/dL) | 0.088 | 0.412 |
| Log-BUN (mg/dL) | 0.037 | 0.728 |
| Log-creatinine (mg/dL) | 0.020 | 0.853 |
| eGFR (mL/min) | −0.054 | 0.612 |
| Log-CRP (mg/dL) | 0.082 | 0.442 |
| Log-insulin (uIU/mL) | 0.049 | 0.649 |
| Log-HOMA-IR | 0.078 | 0.465 |
| Female, n (%) | 0.227 | 0.031* |
| Hypertension, n (%) | 0.115 | 0.281 |
| Diabetes, n (%) | 0.148 | 0.163 |
*P<0.05 was considered statistically significant (two-tailed). Data of triglyceride, glucose, blood urea nitrogen, creatinine, CRP, ANGPTL3, insulin, and HOMA-IR levels showed skewed distribution, and therefore were log-transformed before analysis. HDL-C: High density lipoprotein cholesterol, LDL-C: Low density lipoprotein cholesterol, BUN: Blood urea nitrogen, eGFR: Estimated glomerular filtration rate, CRP: C-reactive protein, HOMA-IR: Homeostasis model assessment of insulin resistance, ANGPTL3: Angiopoietin-like protein 3, ACE: Angiotensin-converting enzyme, ARB: Angiotensin-receptor blocker, CCB: Calcium-channel blocker, BMI: Body mass index