Table 3.

Group Differences in Patient-Reported Outcomes across All Time Points Using Terminal Decline Modeling

Outcome	Four Months Prior to Death*			Six Months Prior to Death*
	Mean	95%CI	P	Mean	95%CI	P
FACT-B			0.386			0.492
Intervention	97.44	93.65, 101.23		98.17	94.74, 101.61
Usual Care	95.11	91.54, 98.68		96.48	93.15, 99.81
HADS-Anxiety			0.587			0.429
Intervention	5.87	4.93, 6.82		5.74	4.87, 6.61
Usual Care	6.23	5.35, 7.12		6.23	5.41, 7.04
HADS-Depression			0.913			0.761
Intervention	5.79	5.08, 6.50		5.65	5.00, 6.29
Usual Care	5.74	5.06, 6.42		5.51	4.88. 6.13

^*Note: We estimated terminal decline and survival distributions with semiparametric models to analyze patient-reported outcomes across all study time points, comparing QOL and symptoms of anxiety and depression between study groups at four and six months prior to death (or prior to date of last follow-up or data cutoff for analysis among those alive). All terminal decline modeling analyses include the patient-reported assessments through week 24 and control for patient age and baseline scores of the outcome variables of interest. FACT-B= Functional Assessment of Cancer Therapy-Breast; HADS=Hospital Anxiety and Depression Scale