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. 2022 Feb 10;17(2):e0263717. doi: 10.1371/journal.pone.0263717

Table 3. Medication use of the female and male patients who received AAD surgery before propensity score matching.

Type A open Type B stent
Variable Female (n = 1,286) Male (n = 2,883) P STD Female (n = 124) Male (n = 549) P STD
Post OP anti-HTN medication
    ACEi/ ARB 429 (33.4) 957 (33.2) 0.917 <0.01 52 (41.9) 255 (46.4) 0.362 -0.09
    Beta blocker 642 (49.9) 1,598 (55.4) <0.001 -0.11 57 (46.0) 304 (55.4) 0.058 -0.19
    CCB 474 (36.9) 1,135 (39.4) 0.124 -0.05 54 (43.5) 250 (45.5) 0.688 -0.04
    Alpha-blocker 59 (4.6) 221 (7.7) <0.001 -0.13 11 (8.9) 65 (11.8) 0.345 -0.10
    Thiazide 46 (3.6) 75 (2.6) 0.083 0.06 9 (7.3) 15 (2.7) 0.014 0.21
    Loop diuretics 327 (25.4) 643 (22.3) 0.027 0.07 18 (14.5) 56 (10.2) 0.165 0.13
    Spironolactone (Potassium-sparing) 54 (4.2) 74 (2.6) 0.005 0.09 2 (1.6) 7 (1.3) 0.767 0.03
    Vasodilator 184 (14.3) 388 (13.5) 0.461 0.02 20 (16.1) 111 (20.2) 0.299 -0.11
    Nitrate 137 (10.7) 286 (9.9) 0.469 0.02 16 (12.9) 85 (15.5) 0.468 -0.07
    Number of anti-HTN drugs 1.8 ± 1.6 1.9 ± 1.6 0.540 -0.02 2.0 ± 1.7 2.1 ± 1.5 0.300 -0.10
Post OP other medication
    Statin 63 (4.9) 116 (4.0) 0.198 0.04 8 (6.5) 59 (10.7) 0.149 -0.15
    Antiplatelet 227 (17.7) 511 (17.7) 0.955 <0.01 31 (25.0) 167 (30.4) 0.232 -0.12
    Anticoagulant 150 (11.7) 401 (13.9) 0.048 -0.07 1 (0.8) 15 (2.7) 0.204 -0.15
    OHA 110 (8.6) 103 (3.6) <0.001 0.21 16 (12.9) 33 (6.0) 0.008 0.24
    Insulin 11 (0.9) 6 (0.2) 0.002 0.09 3 (2.4) 4 (0.7) 0.094 0.14

AAD, acute aortic dissection; STD, standardized difference; OP, operation; HTN, hypertension; ACEi, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker; OHA, oral hypoglycemic agent.

Value are given as number (%) or mean ± standard deviation.