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. 2022 Feb 10;17(2):e0263277. doi: 10.1371/journal.pone.0263277

Table 1. Demographics, substance use, vital signs, and comorbidities at baseline.

N (%)
1,579(100)
Demographics
    Gender
        Female 435(27.55)
        Male 1139(72.13)
    Age (years)
        Mean(SD) 70.5(10)
        Median 71
        (Q1-Q3) (64–78)
        Missing 5
Substance use *
    Tobacco
        Ex/Former smoker 765(48.45)
        No/Unknown 617(39.08)
        Yes 197(12.48)
Vital signs
    Heart rate (bpm)
        N 1011
        Mean(SD) 64.4(22.8)
        Median 68
        (Q1-Q3) (58–78)
        Missing* 568
    Systolic blood pressure (mmHg)
        N 951
        Mean(SD) 141.5(22.2)
        Median 140
        (Q1-Q3) (127–156)
        Missing* 628
     Diastolic blood pressure (mmHg)
        N 951
        Mean(SD) 74.3(13.1)
        Median 73
        (Q1-Q3) (66–82)
        Missing* 628
Comorbidities **
Blood and lymphatic system disorders
        Anemia 290(18.37)
Cardiovascular disorders
        Coronary Heart Disease (CHD) 1579(100)
        Transient Ischemic Attack (TIA) 44(2.79)
        Arterial hypertension 1396(88.41)
                Moderate/severe LV systolic dysfunction 127(8.04)
                Heart Failure 361(22.86)
        Atrial Flutter 270(17.1)
        Atrial fibrillation 212(13.43)
        Heart Valve Disease 659(41.74)
        Peripheral Vascular Disease (PVD) 621(39.33)
                Other/Unknown 595(37.68)
                Peripheral Artery Disease (PAD) 276(17.48)
                        Claudication 137(8.68)
                        Foot or leg cellulitis-osteomyelitis 16(1.01)
                        Other/Unknown 216(13.68)
        Angina 1083(68.59)
                Unstable angina 564(35.72)
                Stable angina 519(32.87)
                Other/Unknown 730(46.23)
Eye disorders
        Diabetic retinopathy 118(7.47)
Endocrine, metabolism, and nutrition disorders
        Hyperlipidemia 638(40.41)
        Hypoglycemia 69(4.37)
        Gout 65(4.12)
        Hyperthyroidism 27(1.71)
        Hypothyroidism 104(6.59)
Gastrointestinal and hepatobiliary disorders
        Chronic liver disease 29(1.84)
Musculoskeletal and connective tissue disorders
        Diabetic foot 9(0.57)
Nervous system disorders
     Diabetic neuropathy 41(2.60)
Psychiatric disorders
     Depression/Anxiety 249(15.77)
Renal and urinary disorders
     CKD (Chronic Kidney Disease) 235(14.88)
Reproductive system and breast disorders
     Erectile dysfunction 35(2.22)
Respiratory, thoracic and mediastinal disorders
          COPD/Asthma 269(17.04)
          Sleep apnea 203(12.86)

* Missing data resulting from extracting laboratory results from unstructured information captured in the EHRs.

** Data indicate single diagnostic labels (i.e., if diagnostic information for a given condition exists multiple times for a single patient, the comorbid condition was counted only once). In addition, a single patient could have been diagnosed with more than one of the analyzed medical conditions.