Table 4. Top-30 recurrent supermotif escape deletions.
| Protein | Deletion location (length) | Number of isolates (number of countries) | M49 areas* | Escape supermotifs** | Affected supertypes*** |
|---|---|---|---|---|---|
| S | Δ145 (1) | 2766 (24) | 16 | 142-GVYYHKNNK-150 | A03 |
| ORF1ab | Δ6343–6429 (87) | 1695 (2) | 2 | 9 | 5 |
| N | Δ363 (1) | 833 (1) | Northern America | 355-KHIDAYKTF-363 | A24 |
| ORF1ab | Δ6338–6436 (99) | 774 (8) | 7 | 2 | A02 |
| ORF1ab | Δ6342–6432 (91) | 705 (3) | 3 | 7 | 3 |
| ORF1ab | Δ6343–6432 (90) | 493 (2) | 2 | 6 | A02, A24 |
| ORF1ab | Δ6343–6431 (89) | 492 (2) | 2 | 6 | A02, A24 |
| ORF1ab | Δ141–143 (3) | 404 (9) | 9 | 135-SYGADLKSF-143 | A24 |
| ORF1ab | Δ6342–6429 (88) | 303 (1) | Northern America | 9 | 6 |
| ORF1ab | Δ7014–7096 (83) | 298 (4) | 4 | 11 | 7 |
| ORF1ab | Δ4714 (1) | 261 (9) | 8 | 4710-STVFPPTSF-4718 | A01 |
| ORF1ab | Δ6341–6432 (92) | 228 (2) | 2 | 6 | 2 |
| ORF1ab | Δ6345–6429 (85) | 200 (1) | Northern America | 8 | 5 |
| ORF1ab | Δ2797–2877 (81) | 173 (2) | 2 | 2 | A03, B44 |
| ORF1ab | Δ6345–6428 (84) | 164 (2) | 2 | 6 | 3 |
| ORF1ab | Δ2276–2356 (81) | 150 (2) | 2 | 4 | 4 |
| ORF1ab | Δ6656–6686 (31) | 150 (1) | Northern America | 6669-AMDEFIERY-6677 | A01 |
| ORF1ab | Δ3705–3705 (1) | 149 (2) | 2 | 3699-TVYDDGARR-3707 | A03 |
| ORF1ab | Δ2796–2877 (82) | 148 (2) | 2 | 3 | A03, B44 |
| ORF1ab | Δ84–85 (2) | 129 (8) | 7 | 2 | 3 |
| ORF1ab | Δ6969–7036 (68) | 126 (4) | 4 | 8 | 4 |
| ORF1ab | Δ2791–2883 (93) | 108 (5) | 5 | 4 | 3 |
| ORF1ab | Δ85 (1) | 107 (3) | 3 | 77-RTAPHGHVM-85 | B62 |
| S | Δ143–144 (2) | 98 (3) | 3 | 142-GVYYHKNNK-150 | A03 |
| ORF1ab | Δ768–862 (95) | 92 (4) | 4 | 12 | 6 |
| ORF1ab | Δ2797–2876 (80) | 92 (2) | 2 | 3 | 2 |
| ORF1ab | Δ6341–6436 (96) | 88 (1) | Northern America | 5 | 4 |
| ORF1ab | Δ6158 (1) | 84 (2) | 2 | 6154-HSIGFDYVY-6162 | 4 |
| ORF1ab | Δ6345–6430 (86) | 83 (1) | Northern America | 7 | 4 |
| ORF1ab | Δ6956 (1) | 81 (6) | 5 | 6954-FIQQKLAL-6961 | B08 |
* If the number of M49 areas is higher than one, the number is given instead.
** If the number of supermotifs with escape deletions is higher than one, the number is given instead.
*** If the number of affected supertypes is higher than two, the number is given instead.