Table 1. Classification of Seurat cluster identity (clustering resolution 0.1) based on differential expression of marker genes.

Cluster (Res. 0.1)	# cells in cluster	Top 10 marker genes by adj. P	Top 10 marker genes by logFC	Annotation
0	17,693	TERF1, PHC1, SEPHS1, UGP2, DPPA4, TBC1D23, JARID2, USO1, ZNF398, LRRC47	DPPA5, DPPA3, GDF3, NANOG, FGF4, POU5F1, CBR3, PRDM14, DPPA2, TRIML2	Pluripotent Cells
1	14,383	TPBG, FGFBP3, FZD3, LIX1, SDK2, BTBD17, DACH1, PLAGL1, DEK, ZNF219	FEZF2, EMX2, LHX2, SOX3, PAX6, WNT7, BARX, SOX1, ZIC1, SIX3	Early Ectoderm
2	3086	TNNI1, COL6A3, COL5A1, RGS4, ACTA2, TMEM88, DOK4, SLC40A1, HAND2, COL3A1	RGS13, LUM, TECRL, DCN, HAND1, PITX1, COL3A1, SLN, IGF2, FIBIN	Mesoderm
3	2673	NR2F1, CNP, S100B, EDNRA, FGFBP3, ATP1A2, DNAJC1, ZEB2, PHACTR3, METRN	MPZ, PRSS56, ROPN1, SOX10, S100B, SCRG1, NPR3, MOXD1, TFAP2B, PHACTR3	Neural Crest
4	2368	S100A16, LGALS3, GATA3, CST3, KRT19, FN1, EPSTI1, DYNLT3, HDHD3, PKP2	APOA2, CST1, APOA1, APOC3, FGB, RBP4, S100A14, TTR, FGA, APOB	Endoderm
5	1990	TAGLN3, RTN1, NHLH1, STMN2, ELAVL2, FNDC5, PCBP4, ELAVL4, DCX, MLLT11	NEUROD1, NHLH1, STMN2, NEUROD4, TBR1, STMN4, NEUROG1, SST, ELAVL3, SLC17A6	Neurons
6	295	EGFL7, GNG11, RAMP2, IGFBP4, PPM1F, RASGRP3, RCSD1, MAP4K2, PLVAP, DOCK6	PLVAP, CD34, CD93, CDH5, DIPK2B, PECAM1, EMCN, CRHBP, ESAM, ECSCR	Endothelial Cells