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. 2022 Feb 10;11:e71361. doi: 10.7554/eLife.71361

Table 2. Top 15 driver genes of each topic from the k = 6 topic model based on Z-score.

Topic Top 15 driver genes
k1 S100A10, FTL, FN1, APOC1, CST3, APOE, SERPINE2, KRT19, CKB, S100A11, LGALS3, TMSB10, S100A16, AFP, PTGR1
k2 MT-CO2, MT-CO3, MT-CO1, MT-CYB, PRDX1, MT-ND4, MT-ATP6, GSTP1, MT-ND1, RPL8, APOE, RPSA, RPL12, PFN1, HMGA1
k3 PTMA, NCL, RPL23, SET, HSP90AB1, TPL27A, MT-ND4, L1TD1, SERBP1, TERF1, HSPD1, CENPF, DPPA4, MT-ATP6, UGP2
k4 S100A10, KRT19, S100A11, VIM, MDK, TMSB10, KRT8, SPARC, COL1A1, FN1, COL1A2, COL6A2, KRT18, TPM1, ANXA2
k5 TUBA1A, VIM, MARCKSL1, MARCKS, TUBA1B, MAP1B, ID3, CRABP1, PTMS, TMSB10, H1FX, STMN1, CENPV, CRABP2, NUCKS1
k6 RPS27, VIM, LDHA, GAPDH, IGFBP2, TUBA1A, APOA1, RPL13, TMSB10, S100A10, RPL6, RPL30, RPL9, RPS19, RPL37