Table 3.
Gene | tagSNPs | Cases (n = 282) | Controls (n = 282) | OR (95% CI) | P value | Model | OR (95% CI) | P value | ||
n | % | n | % | |||||||
| ||||||||||
PNPLA3 | rs738409 (G > C) | |||||||||
GG | 56 | 19.9 | 68 | 24.1 | 1.000 | Dom | 1.160 (0.824–1.615) | 0.424 | ||
GC | 152 | 53.9 | 161 | 57.1 | 1.006 (0.713–1.447) | 0.859 | Rec | 1.492 (1.080–2.066) | 0.016 | |
CC | 74 | 26.2 | 53 | 18.8 | 1.402 (1.026–2.239) | 0.033 | Add | 1.232 (1.003–1.504) | 0.046 | |
MBOAT7 | rs64173 (C > T) | |||||||||
CC | 53 | 18.8 | 64 | 22.7 | 1.000 | Dom | 1.018 (0.778–1.459) | 0.848 | ||
CT | 159 | 56.4 | 167 | 59.2 | 1.003 (0.742–1.359) | 0.979 | Rec | 1.398 (1.053–1.692) | 0.032 | |
TT | 70 | 24.8 | 51 | 18.1 | 1.299 (0.933–1.748) | 0.040 | Add | 1.038 (0.856–1.259) | 0.061 | |
STAT3 | rs744166 (G > A) | |||||||||
GG | 55 | 19.5 | 69 | 24.5 | 1.000 | Dom | 1.193 (0.957–1.491) | 0.398 | ||
GA | 150 | 53.2 | 159 | 56.4 | 1.223 (0.842–1.573) | 0.947 | Rec | 0.682 (0.372–1.195) | 0.019 | |
AA | 77 | 27.3 | 54 | 19.1 | 0.738 (0.469–1.201) | 0.026 | Add | 1.004 (0.894–1.356) | 0.059 | |
TM6SF2 | rs58542926 (C > T) | |||||||||
CC | 60 | 21.3 | 71 | 25.2 | 1.000 | Dom | 0.973 (0.765–1.320) | 0.883 | ||
CT | 155 | 54.9 | 146 | 51.8 | 1.005 (0.782–1.392) | 0.969 | Rec | 0.915 (0.657–1.280) | 0.615 | |
TT | 67 | 23.8 | 65 | 23.0 | 0.928 (0.631–1.336) | 0.655 | Add | 0.952 (0.792–1.169) | 0.699 | |
GATAD2A | rs4808199 (G > A) | |||||||||
AA | 54 | 19.1 | 42 | 14.9 | 1.000 | Dom | 1.042 (0.769–1.415) | 0.789 | ||
AG | 164 | 58.2 | 162 | 57.4 | 0.980 (0.719–1.364) | 0.957 | Rec | 1.687 (0.734–3.897) | 0.217 | |
GG | 64 | 22.7 | 78 | 27.7 | 1.678 (0.719–3.883) | 0.218 | Add | 1.088 (0.836–1.416) | 0.536 |