Table 2. Univariate and multivariate Cox regression for DMFS of patients with HER2 tumours (n = 155).
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Factor | HR (95% CI) | p | HR (95% CI) | p |
| Trastuzumab exposition | ||||
| No | 1 | |||
| Yes | 0.362 (0.167–0.784) | 0.010 | ||
| Trastuzumab exposition | ||||
| ≤292 days/no | 1 | 1 | ||
| >292 days | 0.297 (0.127–0.698) | 0.005 | 0.284 (0.121–0.668) | 0.004 |
| Trastuzumab exposition | ||||
| <6 months/no | 1 | |||
| ≥6 months | 0.333 (0.147–0.756) | 0.009 | ||
| Trastuzumab exposition | ||||
| <12 weeks/no | 1 | |||
| ≥12 weeks | 0.349 (0.158–0.770) | 0.009 | ||
| Trastuzumab exposition | ||||
| ≤9 weeks/no | 1 | |||
| >9 weeks | 0.329 (0.149–0.726) | 0.006 | ||
| St. Gallen Consensus treatment | ||||
| Inadequate | 1 | |||
| Adequate | 0.503 (0.222–1.137) | 0.099 | ||
| pN | ||||
| N− | 1 | 1 | ||
| N+ | 2.226 (1.061–4.671) | 0.034 | 2.370 (1.128–4.981) | 0.023 |