Table 3. Univariate and multivariate Cox regression for OS of patients with HER2 tumours (n = 155).
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Factor | HR (95% CI) | p | HR (95% CI) | p |
| Trastuzumab exposition | ||||
| No | 1 | |||
| Yes | 0.375 (0.160–0.882) | 0.025 | ||
| Trastuzumab exposition | ||||
| ≤292 days/no | 1 | 1 | ||
| >292 days | 0.202 (0.069–0.594) | 0.004 | 0.203 (0.069–0.596) | 0.004 |
| Trastuzumab exposition | ||||
| <6 months/no | 1 | |||
| ≥6 months | 0.249 (0.092–0.670) | 0.006 | ||
| Trastuzumab exposition | ||||
| <12 weeks/no | 1 | |||
| ≥12 weeks | 0.279 (0.110–0.705) | 0.007 | ||
| Trastuzumab exposition | ||||
| ≤9 weeks/no | 1 | |||
| >9 weeks | 0.264 (0.104–0.668) | 0.005 | ||
| St. Gallen Consensus treatment | ||||
| Inadequate | 1 | |||
| Adequate | 0.278 (0.095–0.815) | 0.020 | ||
| pN | ||||
| N0/N1 | 1 | 1 | ||
| N2/N3 | 2.555 (1.166–5.595) | 0.019 | 2.530 (1.155–5.538) | 0.020 |