Table 4. Univariate and multivariate Cox regression for DFS of patients with HER2 tumours (n = 155).
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Factor | HR (95% CI) | p | HR (95% CI) | p |
| Trastuzumab exposition | ||||
| No | 1 | |||
| Yes | 0.451 (0.228–0.891) | 0.022 | ||
| Trastuzumab exposition | ||||
| ≤292 days/no | 1 | |||
| >292 days | 0.372 (0.178–0.778) | 0.009 | ||
| Trastuzumab exposition | ||||
| <6 months/no | 1 | |||
| ≥6 months | 0.396 (0.193–0.811) | 0.011 | ||
| Trastuzumab exposition | ||||
| <12 weeks/no | 1 | |||
| ≥12 weeks | 0.398 (0.197–0.804) | 0.010 | ||
| Trastuzumab exposition | ||||
| ≤9 weeks/no | 1 | 1 | ||
| >9 weeks | 0.375 (0.186–0.757) | 0.006 | 0.353 (0.175–0.714) | 0.004 |
| St. Gallen Consensus treatment | ||||
| Inadequate | 1 | |||
| Adequate | 0.448 (0.210–0.959) | 0.039 | ||
| pN | ||||
| N− | 1 | 1 | ||
| N+ | 2.018 (1.042–3.908) | 0.037 | 2.183 (1.124–4.237) | 0.021 |