Table 2.
Characteristics of gadoxetic acid–enhanced MRI-derived parameters
| Study ID | Quantitative parameter | Quantified liver region | Formula | Interval between MRI and hepatectomy | No. of readers | Blindness to clinical data |
|---|---|---|---|---|---|---|
| Cho 2011 | RLE and remRLE | Whole and FLR | (SIHBP—SIpre)/SIpre | < 4 weeks | 2 | Yes |
| Wibmer 2013 | RLE(%) | Whole | (SIHBP—SIpre)/SIpre * 100 | ≤ 8 weeks | 1 | Yes |
| Sato 2015 | remRE Index | FLR | (SIHBP—SIpre)/SIpre * 100 * remLV | Mean of 20 days | 2 | Unclear |
| Jin 2016 | RLE(%) | Whole | (SIHBP—SIpre)/SIpre * 100 | ≤ 4 weeks | 1 | Yes |
| Costa 2017 | RLE | Whole | (SIHBP—SIpre)/SIpre | ≤ 16 weeks | 1 | Yes |
| Asenbaum 2018 | functFLR | FLR | (FLR(%)*remRLE)/body weight | ≤ 10 weeks | 1 | Yes |
| Chuang 2018 | remCER | FLR | (SIHBP—SIpre)/(SITP—SIpre) | Unclear | Unclear | Unclear |
| Kim 2018 | rHUI-BW | FLR | remLV * ((remSIL20 / SIS20) − 1)/body weight * 1 000 | ≤ 4 weeks | 1 | Yes |
| Theilig 2019 | remRLE | FLR | (SIHBP—SIpre)/SIpre | 14 and 4 days before hepatectomy | 2 | Yes |
| Araki 2020 | FRLV(LMR) | FLR | ((remSIL20 / remSILpre)/(SIM20 / SIMpre)*remLV) /BSA | Unclear | Unclear | Unclear |
| Donadon 2020 | HUI | Whole | LV*(SIL20 / SIS20—1) | Unclear | Unclear | Yes |
| Orimo 2020 | rHUI-BSA | FLR | remLV * ((remSIL20 / SIS20) − 1)/BSA | Unclear | Unclear | Unclear |
| Zhu 2020 | Radiomics | Whole | NA | ≤ 1 week | 2 | Yes |
| Tsujita 2020 | rHUI and HUI | FLR and resected liver |
rHUI = remLV * ((remSIL20 / SIS20) − 1); HUI = rHUI + ((TFLV-remLV)* ((resSIL20 / SIS20) − 1)) |
≤ 8 weeks | 1 | Yes |
| Wang 2020 | RFUR, sRFUR | FLR | NA (based on dynamic contrast enhanced MRI) | ≤ 1 month | 2 | Unclear |
BSA, body surface area; FLR, future liver remnant; FRLV(LMR), functional remnant liver volume corrected by liver-muscle ratio; functFLR, functional FLR; HUI, hepatic uptake index; LV, liver volume; NA, not available; remCER, contrast enhancement ratio of the liver remnant; remLV, the remnant liver volume; remRE Index, relative enhancement index of the liver remnant; remRLE, relative liver enhancement of the liver remnant; remSILpre, signal intensity of the liver remnant before contrast medium injection; remSIL20, signal intensity of the liver remnant at 20 min after contrast medium injection; resSIL20, signal intensity of the resected liver at 20 min after contrast medium injection; rHUI, hepatic uptake index of the liver remnant; rHUI-BSA, rHUI corrected by BSA; rHUI-BW, rHUI corrected by body weight; RFUR, sum of the uptake rate of the remnant liver regions; RLE, relative liver enhancement; SIHBP, liver signal intensity in hepatobiliary phase; SIL20, signal intensity of the liver at 20 min after contrast medium injection; SIM20, signal intensity of the muscle at 20 min after contrast medium injection; SIMpre, signal intensity of the muscle before contrast medium injection; SIpre, liver signal intensity before contrast medium injection; SIS20, signal intensity of the spleen at 20 min after contrast medium injection; SITP, liver signal intensity in transitional phase; sRFUR, sum of the uptake rate of the remnant liver standardized by standard liver volume; TFLV, total functional liver volume