Table 3.
Predictive accuracy of gadoxetic acid–enhanced MRI parameters
| Study ID | Predictor(s) | Cut-off value | Sensitivity (%) | Specificity (%) | AUC (95% CI) | Accuracy (95% CI) |
|---|---|---|---|---|---|---|
| Cho 2011 |
RLE + remRLE |
RLE: 0.84 remRLE: 0.73 |
85.7 |
RLE: 77.3 remRLE: 81.8 |
0.84 |
0.84 (0.65–0.95) |
| Wibmer 2013 | RLE(%) | NA | NA | NA | NA | NA |
| Jin 2016 | RLE(%) | 82.36 | 100 | 54.4 |
0.79 (0.65–0.92) |
NA |
| Costa 2017 | RLE | NA | NA | NA | 0.665 | 0.875 |
| Sato 2015 | remRE Index | NA | NA | NA | NA | NA |
| Chuang 2018 | remCER | 1.23 | 87.5 | 62.6 |
0.78 (0.69–0.85) |
NA |
| Theilig 2019 | remRLE | -0.044 | 75 | 92.6 | 0.854 | NA |
| Araki 2020 | FRLV(LMR) | 615 | 100 (VCoh) | 77.3(VCoh) |
SCoh: 0.939† (0.891–0.987) |
0.808(VCoh) |
| Asenbaum 2018 | functFLR | 8.73 | 94 | 76 |
0.904 (0.803–0.977) |
NA |
| Kim 2018 | rHUI-BW | 12.38 | 94.4 | 90.9 |
0.956 (0.877–0.991) |
NA |
| Donadon 2020 | HUI | 574.33 | 98 | 83 |
0.84 (0.71–0.92) |
NA |
| Orimo 2020 | rHUI-BSA | 0.313 | 75 (VCoh) | 78.12(VCoh) | SCoh: 0.80 | NA |
| Tsujita 2020 | rHUI and rHUI/HUI | NA | NA | NA |
0.962 (0.908–1) † |
NA |
| Zhu 2020 | Radiomics | 0.712 | 93.3 | 77.9 |
0.894 (0.823–0.964) |
0.802 (0.713–0.869) |
| Wang 2020 | sRFUR | 0.0176 | 77.3 | 92.9 |
0.882 (0.809–0.934) |
NA |
† Grade B, C PHLF versus no/grade A PHLF, in which clinical management after operation is altered in grade B, C PHLF while it remains the same in grade A of PHLF; AUC, area under the receiver operating characteristic curve; FLR, future liver remnant; FRLV(LMR), functional remnant liver volume corrected by liver-muscle ratio; functFLR, functional FLR; HUI, hepatic uptake index; PHLF, posthepatectomy liver failure; remCER, contrast enhancement ratio of liver remnant; remRE Index, relative enhancement index of liver remnant; remRLE, RLE of the liver remnant; rHUI, HUI of the liver remnant; rHUI-BSA, rHUI corrected by body surface area; rHUI-BW, rHUI corrected by body weight; RLE, relative liver enhancement; NA, not available; SCoh, study cohort; sRFUR, sum of the uptake rate of the remnant liver standardized by standard liver volume; VCoh, validation cohort