Table 1.
Patient and tumor characteristics in the MIPA study
| Patient or tumor characteristic | MRI group | noMRI group | p |
|---|---|---|---|
| Age at diagnosis—yearsa | 57 ± 11 | 61 ± 11 | < 0.001 |
| Pre- or perimenopausal (%) |
972/2432 (40.0%) |
731/2748 (26.6%) |
< 0.001 |
| Dense breast: ACR density category c or d (%) |
1171/2336 (50.1%) |
831/2503 (33.2%) |
< 0.001 |
| Three or more first-degree relatives with history of breast or ovarian cancer (%) |
35/2432 (1.4%) |
34/2749 (1.2%) |
0.526 |
| BRCA1/2 mutation |
20/2431 (0.8%) |
14/2748 (0.5%) |
0.161 |
| Multifocal/multicentric breast cancer on DMb (%) |
307/2143 (14.3%) |
212/2435 (8.7%) |
< 0.001 |
| Diameter of the largest lesion on DM and/or US—mmc |
16 (11 to 24) |
15 (10 to 21) |
< 0.001 |
| Ductal carcinoma in situ at biopsy (%) |
409/2421 (16.9%) |
472/2554 (18.5%) |
0.255 |
| Invasive lobular histology at biopsy (%) |
341/1959 (17.4%) |
164/2078 (7.9%) |
< 0.001 |
| Triple-negative breast cancer (%) |
103/2234 (4.6%) |
107/2391 (4.5%) |
0.585 |
| Tumor size on final pathology ≥ 20 mm (%) |
799/1886 (42.4%) |
537/1953 (27.5%) |
< 0.001 |
Distributions are given per patient, unless differently specified. Variations of denominators are due to different rates of unknown data
ACR American College of Radiology; DM digital mammography; US ultrasound
a Mean ± standard deviation
b Per-breast distribution
c Per-breast distribution, given as median and interquartile interval