Table 3.

Multivariate correlation analysis; p values were adjusted using the Benjamini–Hochberg correction. Abbreviations: adj., adjusted; DGM, deep grey matter; EDSS, Expanded Disability Status Scale; IRLs, iron rim lesions; LV, lesion volume; nCSA, normalised cross-sectional area; NAGM, normal-appearing grey matter; NAWM, normal-appearing white matter; n.s. not significant

	EDSS baseline		nCSA C1/2
	r	adj. p	r	adj. p
Age	0.36	< 0.001	n.s
Disease duration	0.43	< 0.001	− 0.24	0.002
EDSS baseline	-		− 0.31	0.003
nCSA C1/2	− 0.31	0.003	-
Volume NAGM	− 0.26	0.01	0.2	0.05
Volume NAWM	0.39	< 0.001	0.34	< 0.001
Volume thalamus	− 0.26	0.01	0.41	< 0.001
Volume DGM	n.s		0.36	< 0.001
T2 LV	0.58	< 0.001	− 0.26	0.01
T1 LV	0.5	< 0.001	n.s
IRL volumes	0.48	< 0.001	− 0.31	0.002
Cervical LV	0.56	< 0.001	− 0.21	0.04