Fig. 4.

Effects of image segmentation and feature extraction methodology. Feature reproducibility for ADC (upper row) and T2W-MRI (bottom row) using different segmentation methods (a) and feature extraction packages (b). Each column corresponds to the percentage of features showing excellent (dark green, ICC > 0.90), good (green, 0.90 > ICC > 0. 75), moderate (orange, 0.75 > ICC > 0.5) or poor (red, ICC < 0.5) agreement. In total, 52 features were analyzed, including 14 first-order, 6 shape, 7 gray-level co-occurrence matrix (GLCM), 4 gray-level run-length matrix (GLRLM), 16 gray-level size zone matrix (GLSZM), and 5 neighboring gray-tone difference matrix (NGTDM) features