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Inhibitory activity of compounds in vitro.
| Compounds | IC50 (μM) | Compounds | IC50 (μM) |
|---|---|---|---|
| Lead compound | 10.36 ± 1.03 nM | f | 46.18 ± 1.27 |
| a | 20.17 ± 1.32 | g | 51.48 ± 1.65 |
| b | 26.24 ± 0.56 | h | 84.55 ± 2.50 |
| c | 30.33 ± 0.11 | i | 115.47 ± 13.01 |
| d | 28.47 ± 0.35 | j | 138.27 ± 0.68 |
| e | 43.73 ± 1.07 |
