Table 2.

Summary Incidence of Pleural Mesothelioma by Exposure Route in F344 and Wistar Han Rats.

Strain:	F344			Wistar Han
PM Subtype:	Epithelioid	Biphasic	Combined	Epithelioid	Biphasic	Combined
Exposure Route	# (%)a	# (%)	# (%)a	# (%)a	# (%)a	# (%)a
Feed	1 (0.003)	0 (0)	1 (0.003)	0 (0)	0 (0)	0 (0)
Oral Gavage	5 (0.017)	3 (0.010)	8 (0.027)	0 (0)	0 (0)	0 (0)
Inhalationb	7 (0.037)	7 (0.037)	14 (0.074)	1 (0.083)	1 (0.083)	2 (0.166)
Inhalationb + SC Injection	0 (0)	1 (0.347)	1 (0.347)	0 (0)	0 (0)	0 (0)
Whole bodyc	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
Topical	2 (0.033)	0 (0)	2 (0.033)	0 (0)	0 (0)	0 (0)
Water	3 (0.031)	1 (0.010)	4 (0.041)	0 (0)	0 (0)	0 (0)

Abbreviations: PM, pleural mesothelioma; SC, subcutaneous

^aPercentage of all strain/sex/treatment in cohort (see Supplementary Table 1)

^bWhole body inhalation

^cWhole body exposure to magnetic field or radio frequency radiation