Table 5.
Baseline characteristics of the Florence and Rome external validation cohorts.
| Florence cohort N = 282 | Rome cohort N = 175 | |
|---|---|---|
| Males/Females, n (%) | 164/118 (58/42) | 96/79 (54.9/45.1) |
| Age, years, median (95% CI) | 64 (18–91) | 61 (27–92) |
| Blood counts, median (range) | ||
| Hemoglobin g/dL | 17.6 (15.6–23.5) | 16.6 (12.2-22.2) |
| Platelets x109/L | 476 (190–890) | 468 (99-1320) |
| WBC x109/L | 9.4 (4.5–18.9) | 9.7 (3.7–44.4) |
| Neutrophils % | 71.9 (43.4–91.3) | |
| Lymphocytes % | 18.7 (5.3–44.5) | |
| NLR | 3.5 (0.6–16.3) | 3.83 (0.98–16.95) |
| At least one CV risk factor, n (%) | 164 (58) | 103 (58.9) |
| Previous arterial thrombosis, n (%) | 37 (13.1) | 17 (9.7) |
| Previous venous thrombosis, n (%) | 33 (11.7) | 16 (9.1) |
| Treatments, n (%) | ||
| Phlebotomy | 282 (100) | 151 (86.3) |
| Hydroxyurea | 175 (62) | 116 (66.3) |
WBC white blood cells, NLR neutrophil/lymphocyte ratio, CV cardiovascular.