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Summary of the most relevant findings of CTEPH-EC in comparison with PAH-EC.
| CTEPH-EC | |
|---|---|
| HOXD (mRBNA) | = |
| Glycolysis (mRNA) | ↓ |
| PDHA1 (mRNA) | ↓ |
| Glutaminolysis (mRNA) | ↓ |
| Oxidative phosphorylation complexes (protein) | ↓ |
| Basal viability | ↓ |
| Viability upon 3PO, BPTES and DCA treatment | ↑ |
