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. 2022 Feb 10;9:5. doi: 10.1038/s41439-022-00181-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A The number of positive major features listed in the diagnostic criteria¹⁸. Patients with a PTC were significantly more likely to manifest the major symptoms of the diagnostic criteria than those without a PTC. B There was no significant difference in the maximum diameter of AML with or without a PTC. C Although there was no statistically significant difference in the age of onset of AML between patients with and without a PTC, there was a tendency for patients with a PTC to develop AML at a younger age. D An onset under 20 years of age was defined as early onset, while an onset over 20 years of age was defined as late onset. There was no statistically significant difference, but the percentage of early onset was higher in patients with a PTC. E, F Although not statistically significant, the percentage of multiple and bilateral cases was higher in patients with a PTC.