Table 3.

Characteristics of included studies on hospitalization risk in Crohn’s Disease

Study	Country	Data Source	Study Span (Year)	Sample Size	Age Group	Sex (%)	Location at Diagnosis (%)	Perianal Disease (%)	Behavior at Diagnosis (%)	Time Intervals Reported (Years)	Type of Hospitalization
Biroulet et al, 2010	USA	Olmsted County	1970 – 2004	310	All Ages	-	-	-	-	5, 10, 30	All-cause
Burisch et al, 2018	Multiple European Countries	EPI-IBD	2010	488	Adults	M (50), F (50)	L1 (27), L2 (28), L3 (23), L4 (6)	9	B1 (71), B2 (21), B3 (8)	1, 3, and 5	All-cause and CD-related
Golovics et al, 2015	Hungary	Veszprem Province	2000 – 2010	331	-	M (53), F (47)	L1 (35), L2 (32), L3 (33), L4 (1)	17.8	B1 (55), B2 (20), B3 (25)	1, 3, and 5	All-cause and CD-related
Jeuring et al, 2017	Netherlands	IBD-SL	1991 – 2011	1162	Adults	M (37), F (63)	L1 (43), L2 (32), L3 (23), L4 (2)	8.1	B1 (82), B2 (12), B3 (6)	1, 3, 5, and 10	CD-related
Niewiadomski et al, 2015	Australia	Barwon Area	2007 – 2008, 2010 – 2013	146	All Ages	M (47), F (53)	L1 (32), L2 (30), L3 (38), L4 (-)	12	B1 (80), B2 (10), B3 (10)	1 and 5	All-cause
Verdon et al, 2020	Canada	RAMQ	1996 – 2015	20644	All Ages	M (43), F (57)	-	-	-	5	All-cause

M: Male, F: Female, L1: Ileal, L2: Colonic, L3: Ileocolonic, L4: Upper GI Tract, B1: Inflammatory, B2: Fibrostenotic, B3: Penetrating, CD: Crohn’s Disease