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Average number of epitopes in the Wuhan-1 and Omicron spike protein sequences predicted for HLA class I alleles including in the 12 HLA class I supertypes. The median value is indicated. Box limits indicate the interquartile range. Whiskers are adjusted to maximal and minimal values. The number of epitopes in the Wuhan-1 (black) and Omicron (red) strains predicted for HLA class I alleles including in the 6 HLA-A and 6 HLA-B supertypes are depicted in panels (A, B), respectively.
