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. 2022 Jan 28;11:823054. doi: 10.3389/fonc.2021.823054

Table 3.

Univariate and multivariate analyses of prognostic factors for overall survival of patients.

Variable Univariate Multivariate
OS HR (95% CI) p OS HR (95% CI) p
Age (years) 1.013 (0.991–1.035) 0.250
Sex (male/female) 0.972 (0.5340–1.770) 0.926
HBsAg positive 0.697 (0.425–1.141) 0.151
Cirrhosis 1.205 (0.763–1.902) 0.425
CRP (mg/L) 1.018 (1.005–1.032) 0.007 0.994 (0.975–1.014) 0.561
AFP (ng/mL) 1.159 (0.675–1.992) 0.592
Child–Pugh grade (A/B) 2.587 (1.511–4.428) 0.001 0.700 (0.237–2.069) 0.519
Tumor diameter (cm) 1.025 (1.003–1.046) 0.023 1.100 (1.011–1.197) 0.026
Vascular invasion 0.302 (0.188–0.486) <0.001 0.828 (0.395–1.737) 0.617
Tumor stage (I and II/III) 0.388 (0.199–0.757) 0.005 0.149 (0.061–0.365) <0.001
Degree of differentiation 2.105 (1.277–3.468) 0.004 3.684 (1.978–6.861) <0.001
Intraoperative blood loss (mL) 1.000 (1.000–1.001) 0.050
PNI (≥43.75/<43.75) 6.176 (3.523–10.862) <0.001 5.081 (2.209–11.688) <0.001
NLR (≥3.29/<3.29) 0.283 (0.176–0.455) <0.001 0.510 (0.272–0.957) 0.036