Table 4.
Univariate and multivariate analyses of prognostic factors for recurrence-free survival of patients.
| Variable | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | |
| Age (years) | 1.003 (0.984–1.023) | 0.738 | ||
| Sex (male/female) | 0.883 (0.507–1.535) | 0.658 | ||
| HBsAg positive | 1.287 (0.817–2.028) | 0.276 | ||
| Cirrhosis | 1.171 (0.778–1.764) | 0.450 | ||
| CRP (mg/L) | 1.015 (1.002–1.029) | 0.027 | 0.988 (0.968–1.007) | 0.218 |
| AFP (ng/mL) | 0.784 (0.483–1.272) | 0.324 | ||
| Child–Pugh grade (A/B) | 0.314 (0.190–0.517) | <0.001 | 0.775 (0.290–2.071) | 0.611 |
| Tumor diameter (cm) | 1.015 (0.997–1.033) | 0.096 | ||
| Vascular invasion | 0.379 (0.244–0.589) | <0.001 | 0.513 (0.277–0.952) | 0.034 |
| Tumor stage (I and II/III) | 0.136 (0.073–0.256) | <0.001 | 0.184 (0.059–0.569) | 0.003 |
| Degree of differentiation | 1.404 (0.932–1.886) | <0.001 | 2.836 (1.593–5.050) | <0.001 |
| Intraoperative blood loss (mL) | 1.000 (1.000–1.001) | 0.279 | ||
| PNI (≥43.75/<43.75) | 3.846 (2.451–6.035) | <0.001 | 6.530 (3.456–12.338) | <0.001 |
| NLR (≥3.29/<3.29) | 0.448 (0.296–0.679) | <0.001 | 0.972 (0.435–2.170) | 0.944 |