Table 2.
Cancer family history.
| Total (%) n = 370 (100%) | Not Pathogenic (%) n = 313 (85%) | Pathogenic (%) n = 57 (15%) | Univariate Analysis p-value | |
|---|---|---|---|---|
| Median Number of Breast Cancer Cases in the Family up to Third Degree, excluding proband (IQR) | 1 (0–2) | 1 (0–2) | 1 (0–2) | 0.0402 |
| At least 1 Cancer in the Family up to Third Degree, including proband: | ||||
| Male Breast | 4 (01) | 4 (01) | 0 (00) | ns |
| Ovary | 35 (09) | 26 (08) | 9 (16) | ns |
| Pancreas | 34 (09) | 25 (08) | 9 (16) | ns |
| Prostate | 79 (21) | 67 (21) | 12 (21) | ns |
| Melanoma | 26 (07) | 20 (06) | 6 (11) | ns |
| Sarcoma | 12 (03) | 7 (02) | 5 (09) | 0.0105 |
| Adrenocortical | 0 (00) | 0 (00) | 0 (00) | NA |
| Central Nervous System | 28 (08) | 24 (08) | 4 (07) | ns |
| Leukemia | 29 (08) | 27 (09) | 2 (04) | ns |
| Gastric | 37 (10) | 34 (11) | 3 (05) | ns |
| Colon | 93 (25) | 78 (25) | 15 (26) | ns |
| Endometrium | 8 (02) | 6 (02) | 2 (04) | ns |
| Thyroid | 30 (08) | 24 (08) | 6 (11) | ns |
| Kidney | 14 (04) | 10 (03) | 4 (07) | ns |
IQR, interquartile range; ns, not significant; NA, not applicable.