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. 2022 Jan 28;12:809359. doi: 10.3389/fneur.2021.809359

Table 2.

Demographics, disease characteristics, grade of axonal damage, and European Federation of Neurological Societies/Peripheral Nerve Society (EFNS/PNS) criteria of all subgroups.

Typical CIDP DADS Diabetic Oxaliplatin induced Idiopathic neuropathy
(n = 67) (n = 28) neuropathy induced associated with restless
neuropathy (n = 40) legs syndrome (n = 12) (n = 30)
Gender, male/female 54/22 26/2 19/21 7/5 10/20
Age at examination, mean, SD 59 ±13 60 ±11 68 ±11 65 ±6 64 ±18
Disease duration from diagnosis until examination (months), median, range 31 0–295 21 0–118 128 3–366 1 0–5 89 0–397
INCAT-ODSS at time of examination, median, range 2 0–9 2 0–6 n.a. n.a. n.a. n.a. n.a. n.a.
Grade of axonal damage *, n, %
   Slight 10 15% 2 7% 7 18% 5 42% 10 33%
   Moderate 34 51% 19 68% 19 48% 6 50% 12 40%
   Severe 18 27% 7 25% 7 18% 1 8% 6 20%
   No amplitudes detectable 5 8% 0 0% 7 18% 0 0% 1 3%
EFNS/PNS criteria at timepoint of ultrasound examination, n, %
   Not fulfilled 17 25% 4 14% 29 73% 9 75% 19 63%
   Possible 16 24% 7 25% 10 25% 2 17% 11 37%
   Probable 10 15% 7 25% 1 3% 1 8% 0 0%
   Definite 24 36% 10 36% 0 0% 0 0% 0 0%

INCAT-ODSS, inflammatory neuropathy cause and treatment overall disability score.

*

Grading of axonal damage.

Slight axonal damage: 71 to <100 % of the lower limit of the reference amplitude.

Moderate axonal damage: 41–70 % of the lower limit of the reference amplitude.

Severe axonal damage: 11–40 % of the lower limit of the reference amplitude.

No CMAP or SNAP amplitude detectable: <10 % of the lower limit of the amplitude of the reference values.