Table 2.
Typical CIDP | DADS | Diabetic | Oxaliplatin induced | Idiopathic neuropathy | ||||||
---|---|---|---|---|---|---|---|---|---|---|
(n = 67) | (n = 28) | neuropathy | induced | associated with restless | ||||||
neuropathy (n = 40) | legs syndrome (n = 12) | (n = 30) | ||||||||
Gender, male/female | 54/22 | 26/2 | 19/21 | 7/5 | 10/20 | |||||
Age at examination, mean, SD | 59 | ±13 | 60 | ±11 | 68 | ±11 | 65 | ±6 | 64 | ±18 |
Disease duration from diagnosis until examination (months), median, range | 31 | 0–295 | 21 | 0–118 | 128 | 3–366 | 1 | 0–5 | 89 | 0–397 |
INCAT-ODSS at time of examination, median, range | 2 | 0–9 | 2 | 0–6 | n.a. | n.a. | n.a. | n.a. | n.a. | n.a. |
Grade of axonal damage *, n, % | ||||||||||
Slight | 10 | 15% | 2 | 7% | 7 | 18% | 5 | 42% | 10 | 33% |
Moderate | 34 | 51% | 19 | 68% | 19 | 48% | 6 | 50% | 12 | 40% |
Severe | 18 | 27% | 7 | 25% | 7 | 18% | 1 | 8% | 6 | 20% |
No amplitudes detectable | 5 | 8% | 0 | 0% | 7 | 18% | 0 | 0% | 1 | 3% |
EFNS/PNS criteria at timepoint of ultrasound examination, n, % | ||||||||||
Not fulfilled | 17 | 25% | 4 | 14% | 29 | 73% | 9 | 75% | 19 | 63% |
Possible | 16 | 24% | 7 | 25% | 10 | 25% | 2 | 17% | 11 | 37% |
Probable | 10 | 15% | 7 | 25% | 1 | 3% | 1 | 8% | 0 | 0% |
Definite | 24 | 36% | 10 | 36% | 0 | 0% | 0 | 0% | 0 | 0% |
INCAT-ODSS, inflammatory neuropathy cause and treatment overall disability score.
Grading of axonal damage.
Slight axonal damage: 71 to <100 % of the lower limit of the reference amplitude.
Moderate axonal damage: 41–70 % of the lower limit of the reference amplitude.
Severe axonal damage: 11–40 % of the lower limit of the reference amplitude.
No CMAP or SNAP amplitude detectable: <10 % of the lower limit of the amplitude of the reference values.