Table 2.
Reported Synthetic Autoantibody Decoys/Autoantigen Mimics.
| Autoantigen/Disease | aAb | Decoy molecule | Reference |
|---|---|---|---|
| Insulin Receptor/extreme insulin resistance Type B | MA20 | RNA | (21) |
| DS DNA/Lupus nephritis | R4A | Peptide/HIV protease inhibitor compound | (5, 20) |
| Acetylcholine Receptor/Myasthenia Gravis | Mab 198 | RNA/Peptide | (22–24) |
| ß2-glycoprotein-1/Antiphospholipid syndrome | aPL | Peptide/platelets | (25) |
| Myelin associated glycoprotein (MAG)/Multiple Sclerosis | Anti-MAG IgM | Peptide/glycopolymer | (26) |
| Collagen type 17/Bullous Pemphigoid | Anti-COL17 | Peptide | (27) |
| Angiotensin 1 receptor/Hypertension | Anti-AT1R | Peptide | (26) |
| Thyrotropin Receptor/Hypothyrodism | Anti-TSHR | Exosomes | (28) |
| Platelet Membrane/Autoimmune Thrombocytopenia | Anti-Platelet | Platelet Membrane-coated nanoparticles | (29) |