TABLE 1.
The REVERT trial – Primary and secondary outcomes.
| Outcome | Standard VM |
Modified VM |
Effect size |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n (214) | % | Median | IQR | n (214) | % | Median | IQR | OR | 95% CI | Median | IQR | p | |
| Presence of sinus rhythm at 1 min | 37 | 17 | - | - | 93 | 43 | - | - | 3.7 | 2.3–5.8 | - | - | < 0.0001 |
| Adenosine needed | 148 | 69 | - | - | 108 | 50 | - | - | 0.45 | 0.30–0.68 | - | - | 0.0002 |
| Any other emergency anti-arrhythmic needed | 171 | 80 | - | - | 121 | 57 | - | - | 0.33 | 0.21–0.51 | - | - | < 0.0001 |
| Discharged home from emergency room | 146 | 68 | - | - | 134 | 63 | - | - | 0.79 | 0.51–1.21 | - | - | 0.28 |
| Any adverse events | 8 | 4 | - | - | 13 | 6 | - | - | 1.61 | 0.63–4.08 | - | - | 0.32 |
| Time spent in emergency room (h) | - | - | 2.83 | 1.05–3.62 | - | - | 2.82 | 1.95–3.77 | - | - | 0.90 | 0.75–1.10 | 0.31 |
Source: Adapted from Appelboam A, Reuben A, Mann C, et al. Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT): A randomised controlled trial. Lancet. 2015;386(10005):1747–1753. https://doi.org/10.1161/01.CIR.98.24.2716
VM, Valsalva manoeuvre; CI, confidence interval; IQR, interquartile range; OR, odds ratio.