TABLE 1.
Type of endocrine disrupting chemicals | Endocrine disrupting chemicals | Sources of exposure | Industrial benefits | Potential gynecologic health risks | References |
Persistent EDCs | Dioxins | Combustion, waste incineration, volcanic eruptions, forest fires | N/A | Endometriosis, adenomyosis, reproductive cancers |
Fouzy et al. (2007), Bruner-Tran and Osteen (2010), Bruner-Tran et al. (2016), Kishi et al. (2017) |
Polychlorinated Biphenyls (PCBs) | Electrical transformers, microscope immersion oils, pesticides, carbonless copy paper | Electrical insulating compounds | Endometriosis, adenomyosis, uterine fibroids | Rier et al. (2001), Heilier et al. (2004), Trabert et al. (2015) |
|
Non-persistent EDCs | Bisphenol A (BPA)/ Bisphenol S (BPS) |
Children’s toys, water bottles, canned food liners, dental sealants, receipt coatings | Plasticizer and epoxy resins | Endometriosis, uterine fibroids, polycystic ovarian syndrome, adenomyosis |
Newbold et al. (2007), Cobellis et al. (2009), Kandaraki et al. (2011), Bariani et al. (2020) |
Phthalates | Cosmetics, medical equipment, medications, paints, adhesives, personal care products | Plasticizers, solvents, and stabilizers | Endometriosis, uterine fibroids, adenomyosis |
Duty et al. (2005), Huang et al. (2010), Bariani et al. (2020) |
|
Parabens | Cosmetics, pharmaceutical products | Preservatives | Endometriosis, uterine fibroids | Bariani et al. (2020), Peinado et al. (2021) | |
Triclosans (TCSs) | Hand sanitizers, mouth wash, toothpaste | Antimicrobial properties | Polycystic ovarian syndrome | Ye et al. (2018) |