Table 1.

Demographic and clinical characteristics of patients with AD and healthy controls.

Characteristics	AD (n = 463)	Controls (n = 1,389)	p-value
Male, n (%)	231 (49.9)	693 (49.9)	1
Age at examination, yr	69.00 ± 11.31	69.08 ± 11.28	0.9016
BMI	22.36 ± 3.63	22.58 ± 3.89	0.8321
eGFR (ml/min)	101.13 ± 21.16	104.76 ± 19.53	0.5961
APOE 4 allele carriers (%)	33.48%
Serum cystatin C (mg/l)	1.034 ± 0.254	1.010 ± 0.248	P = 0.0362
MMSE	15.92 ± 7.33	27.18 ± 3.23	p < 0.001
MoCA	10.33 ± 6.45	24.98 ± 1.13	p < 0.001
Age at onset, yr	67.58 ± 10.12
Disease duration, mo	17.61
CDR staging (0.5 or 1/2/3)	148/163/152
MMSE according to CDR staging	22.88 ± 2.93/15.47 ± 3.29/6.68 ± 3.33
MoCA according to CDR staging	17.65 ± 4.22/10.19 ± 3.35/5.25 ± 2.85

yr, year; mo, month; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment (MoCA); CDR, clinical dementia rating. The meaning of the bold values is P < 0.05.